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在后天性重症肌无力(MG)中,单纯肢带肌受累者少见。本文报告在314例MG中发现的12例(3.8％)慢性肢带型MG病人,男2例女10例,年龄29～76岁,诊断前病程4个月～7年。7例Ⅱ_A型,5例Ⅱ_B型。全组病人在检查时或随访期间均有突出的近端肌无力(多在下肢),而无一有眼肌麻痹、球麻痹或肌无力危象。其诊断均依据其临床特点、对胆碱酯酶抑制剂的阳性反应,以及重复神经电刺激(RNS)有明显的衰减反应。
In acquired myasthenia gravis (MG), patients with simple limb muscle involvement are rare. This article reports 12 cases (3.8%) of chronic limb MG patients found in 314 cases of MG. There are 10 males and 2 females, aged 29-76 years, with a history of 4 months to 7 years before diagnosis. 7 cases of type Ⅱ_A, 5 cases of type Ⅱ_B. All patients in the examination or follow-up period have prominent proximal muscle weakness (mostly in the lower limbs), and none of the ophthalmoplegia, paralysis of the ball or myasthenic crisis. Its diagnosis is based on its clinical features, the positive reaction of cholinesterase inhibitors, and repeated electrical nerve stimulation (RNS) significantly decay reaction.