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近年来,由于广泛接种流行性脑脊髓膜炎菌苗,本市流行性脑脊髓膜炎的发病率已大大降低。过去死亡率很高的暴发型流行性脑脊髓膜炎败血症(下简称暴脑败)亦相应地减少。自提高了对微循环的认识后,采用了舒血管药物抢救本病休克型的治疗方案,病死率不断下降。又由于对弥漫性血管内凝血(下称DIC)有了较多的研究,采用了肝素综合疗法,有效地防止了出血倾向,所谓华弗氏综合征(即肾上腺皮质出血)的抢救亦收到较好的效果。我院在1974～1976年5月间用肝素综合疗法治疗15例“暴脑败”,仅1例因心力衰竭而死亡。兹将我院抢救15例的经验与教训分述如下。
In recent years, due to the widespread vaccination of epidemic meningitis vaccine, the incidence of meningococcal disease in our city has been greatly reduced. In the past, the outbreak of epidemic meningococcal septicemia (hereinafter referred to as the “brain failure”) with a high mortality rate was also correspondingly reduced. Since raising awareness of the microcirculation, the use of vasodilator drugs to rescue the disease shock-type treatment programs, mortality rates continue to decline. And because of diffuse intravascular coagulation (hereinafter referred to as DIC) have more research, the use of heparin therapy, to effectively prevent the tendency of bleeding, the so-called Warf’s syndrome (ie, adrenal hemorrhage) rescue also received Better effect. In our hospital from 1974 to May 1976 with heparin therapy in 15 cases of “storm defeat”, only 1 case of death due to heart failure. I will rescue 15 cases of hospital experience and lessons are as follows.