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目的:结合临床实践经验,开展欣母沛治疗产后出血的临床分析。方法:选取东阳市妇幼保健院2008年1月～2009年12月期间87例产后出血患者为研究对象,采用回顾性研究,将患者的病例资料、临床治疗资料等搜集整理,并与经治医师、责任护士共同探讨病例,探讨欣母沛治疗产后出血的临床疗效,采用Microsoft Excel建立数据库,运用SPSS 13.0统计软件进行统计分析。结果:①疗效:欣母沛注射后,显效80例,阴道出血立即减少,有效5例,30 min内出血减少,总有效率97.70%。2例无效,术中行全子宫切除,病理检查结果显示为植入性胎盘。②药物剂量关系:85例有效患者中,80例为单次注射出血量均减少,5例经两次及多次注射后阴道出血减少,2例无效患者为多次注射无效。③出血量:所有患者中,78例出血量500～1 000 ml,7例出血量为1 000～2 000 ml,无效的2例出血量均在2 000 ml以上。④不良反应:87例患者中8例出现1种或1种以上不良反应,发生率为9.20%,一般在48 h内可缓解。结论:欣母沛可有效扼制宫缩乏力性产后出血,具有高效、安全、方便、迅速等优点,可作为产后出血治疗的首选药物,值得临床推广应用。
OBJECTIVE: To analyze clinical experience of Xin Maopei in treating postpartum hemorrhage based on clinical practice. Methods: Dongyang City, MCH January 2008 - cases of postpartum hemorrhage during the December 87, 2009 for the study, retrospective study, the collection and collation of patient clinical data, clinical data, etc., and with the treating physician , Responsible nurses to discuss the cases together and explore the clinical curative effect of Xin-Pei-Pei on postpartum hemorrhage. The database was set up by using Microsoft Excel and the statistical analysis was made by using SPSS 13.0 statistical software. Results: ①Effect: Xinma Pei injection, markedly effective in 80 cases, immediately reduced vaginal bleeding, effective in 5 cases, 30 min reduced bleeding, the total effective rate was 97.70%. 2 cases were ineffective, hysterectomy line surgery, pathological examination showed that the placenta accreta. ② drug dose relationship: 85 cases of effective patients, 80 cases of a single injection of blood loss were reduced in 5 cases after two and multiple injections of vaginal bleeding decreased, two cases of ineffective in patients with multiple injections invalid. ③ Bleeding amount: In all patients, 78 cases of bleeding amount was 500 ~ 1 000 ml, 7 cases of bleeding amount was 1 000 ~ 2 000 ml, 2 cases of invalid blood loss were more than 2 000 ml. ④ Adverse reactions: One or more of the 87 patients showed one or more adverse reactions, the incidence was 9.20%, which was generally relieved within 48 hours. Conclusion: Xin-Pei can effectively curb uterine inertia postpartum hemorrhage, with the advantages of high efficiency, safety, convenience, rapidity, etc., which can be used as the drug of choice for the treatment of postpartum hemorrhage, which is worthy of clinical application.