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目的观察乳腺癌保乳手术及哨兵淋巴结活检的临床疗效。方法 62例临床确诊的早期乳腺癌患者,均行区段切除及哨兵淋巴结活检手术,其中10例哨兵淋巴结阳性者加腋淋巴结清扫术,术后行根治性放疗,并根据临床评价38例行辅助化疗,36例内分泌治疗。结果术后随访24～106个月,中位随访53个月,1例3年内复发,2例5年内复发,局部复发率4.8%。复发者均改行乳腺癌改良根治术。结论对于临床早期乳腺癌患者,保留乳房及哨兵淋巴结活检术可行,术后辅以放疗、化疗及内分泌治疗能够获得满意效果。
Objective To observe the clinical efficacy of breast conserving surgery and sentinel lymph node biopsy. Methods Sixty-two patients with clinically diagnosed early-stage breast cancer underwent radical resection and sentinel lymph node biopsy. Ten sentinel lymph node-positive patients underwent axillary lymph node dissection. Radiotherapy was performed postoperatively and 38 patients were assisted by clinical evaluation Chemotherapy, 36 cases of endocrine therapy. Results The patients were followed up for 24 to 106 months. The median follow-up time was 53 months. One case relapsed within three years, two cases relapsed within five years and the local recurrence rate was 4.8%. Recurrences were switched to modified radical mastectomy. Conclusions Breast and sentinel lymph node biopsy are feasible for patients with early stage breast cancer in clinical practice. Postoperative adjuvant radiotherapy, chemotherapy and endocrine therapy can achieve satisfactory results.