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目的观察四磨汤口服液干预早中期早产儿喂养不耐受(FI)的临床疗效。方法将169例早中期早产儿随机分为干预组83例和对照组86例,2组均给予常规综合治疗,干预组在此基础上给予四磨汤口服液,治疗7 d后比较2组的临床疗效。结果干预组频繁呕吐、奶量不增或减少、胃潴留、FI发生率均低于对照组,经统计学分析,差异均有统计意义(P<0.05);干预组恢复出生体质量时间、达全胃肠喂养时间均短于对照组,差异均有统计意义(P<0.05);干预组未见皮疹,药物热,大便性状改变,肝、肾功异常等不良反应。结论四磨汤口服液干预早中期早产儿FI疗效显著,可降低FI的发生率,且无明显不良反应,适合在临床推广应用。
Objective To observe the clinical effect of Si mill-tang oral solution on early-middle-aged preterm infants intolerance (FI). Methods A total of 169 early-to-middle-stage preterm infants were randomly divided into intervention group (83 cases) and control group (86 cases). Both groups were given conventional comprehensive treatment. On the basis of this, SIJT oral liquid was given to the intervention group. After 7 days of treatment, Clinical efficacy. Results In the intervention group, frequent vomiting, no increase or decrease in milk volume, gastric retention, and FI were significantly lower than those in the control group (P <0.05), and the difference was statistically significant (P <0.05) Total gastrointestinal feeding time were shorter than the control group, the difference was statistically significant (P <0.05); the intervention group, no rash, drug fever, stool traits, abnormal liver and kidney function and other adverse reactions. Conclusion Simotang oral solution intervention in early and midterm premature infants FI significant effect, can reduce the incidence of FI, and no significant adverse reactions, suitable for clinical application.