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Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is characterized by fibro-fatty replacement of the right ventricle.However,the feasibility and significance of myocardial fibrosis detec-ted by delayed enhancement (DE) using 3.0T magnetic resonance imaging (MRI) in.ARVD /C is seldomly studied.Methods Twenty-seven consecutive patients were prospectively evaluated for ARVD /C.Magnetic reso-nance imaging was performed on a 3.0T scanner.Ten minutes after intravenous administration of 0.2 mmol /kg of gadodiamide,DE-MRI was obtained.Diagnosis of ARVD /C was based upon the Task Force criteria and in-cluded MRI findings.Results Seventeen(59% ) of 27 patients met the Task Force criteria for ARVD /C.Right ven-tricle DE was found in all (100% ) ARVD /C patients compared with none (0%) of the 10 patients without ARVD /C (P <0.001) .Additional left ventricular DE was found in 8/17 ARVD/C patients while without left ventricular mor-phological and functional abnormalities detected by echocardiography or MRI.Conclusions DE using 3.0T MRI could effectively detect myocardial fibrosis in the right and left ventricular myocardium in ARVD /C patients.Detection of myocardial fibrosis may have an important clinical significance in ARVD/C diagnosis.Histological left ventricle in-volvement may be easily missed by echocardiography.
Nearly the feasibility and significance of myocardial fibrosis detec-ted by delayed enhancement (DE) using 3.0T magnetic resonance imaging (MRI) in. ARVD / C is seldomly studied. Methods Twenty-seven consecutive patients were prospectively evaluated for ARVD /C.Magnetic reso-nance imaging was performed on a 3.0T scanner. Ten minutes after intravenous administration of 0.2 mmol / kg of gadodiamide, DE MRI was obtained. Diagnosis of ARVD / C was based upon the Task Force criteria and in-cluded MRI findings. Results Seventeen (59%) of 27 patients met the Task Force criteria for ARVD /C.Right ven- tricle DE was found (0%) of the 10 patients without ARVD / C (P <0.001). Additional left ventricular DE was found in 8/17 ARVD / C patients while without left ventricular mor -phological and functional abnormalities detected by Echocardiography or MRI. Confractive DE using 3.0T MRI could effectively detect myocardial fibrosis in the right and left ventricular myocardium in ARVD / C patients. Detection of myocardial fibrosis may have an important clinical significance in ARVD / C diagnosis. Histological left ventricular in-volvement may be easily missed by echocardiography.