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对血浆纤溶系统活性与脑梗死再发的关系进行了探讨，旨在为脑梗死的二级预防提供一定的理论依据。采用发色底物法对５０例脑再梗死患者及１２１例随访未再发的初次脑梗死患者的组织型纤溶酶原激活物（ｔ－ＰＡ）活性及纤溶酶原激活物抑制物（ＰＡＩ）活性进行了测定。结果表明，脑再次梗死组ＰＡＩ活性显著高于初次脑梗死组，而ｔ－ＰＡ活性在两组之间无显著差异。提示ＰＡＩ活性升高可能是脑梗死再发的危险因素之一。
The relationship between fibrinolytic system activity and recurrence of cerebral infarction was discussed in order to provide a theoretical basis for secondary prevention of cerebral infarction. Tissue plasminogen activator (t-PA) activity and plasminogen activator inhibitor (t-PA) activity in 50 patients with cerebral infarction and 121 patients with primary cerebral infarction PAI) activity was measured. The results showed that PAI activity in cerebral infarction group was significantly higher than that in primary cerebral infarction group, while t-PA activity was no significant difference between the two groups. Tip PAI activity may be one of the risk factors for recurrent cerebral infarction.