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中线恶性网织细胞增多症（Midlinemalignantreticulosis，MMR）简称中线恶网，既往亦称恶性肉芽肿。1978年WHO将其定义为一种进行性破环的非结核样肉芽肿性损伤，局限在鼻腔、鼻窦及腭部，并浸润周围的骨质及软组织。其破坏性甚于恶性肿瘤，早期症状无特异性，病理检查多为慢性
Midline malignant reticulosis (MMR) is referred to as the midline malignancy, also known as malignant granuloma. In 1978 the WHO defined it as a progressive destruction of non-tuberculous granulomatous lesions confined to the nasal cavity, paranasal sinuses and ankles, and infiltrated the surrounding bone and soft tissue. It is more destructive than malignant tumors. The early symptoms are non-specific. The pathological examination is mostly chronic.