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目的 探讨异常妊娠史与宫内巨细胞病毒感染的关系。方法 应用聚合酶链反应(PCR) 技术,对羊水标本进行巨细胞病毒检测。结果 研究组162 例,检出阳性41 例,阳性率为25 .31 % (41/162) ;正常对照组106 例,检出阳性4 例,阳性率为3 .77 % (4/106) ;两组之间有显著差异( P< 0 .01) 。结论 异常妊娠史孕妇再次感染巨细胞病毒可能性较大,应孕前查明原因,早期诊断、早期治疗,以减少病儿的再次出生。
Objective To investigate the relationship between abnormal pregnancy history and intrauterine cytomegalovirus infection. Methods Polymerase chain reaction (PCR) was used to detect cytomegalovirus in amniotic fluid samples. Results The study group of 162 cases, 41 were positive, the positive rate of 25. 31% (41/162). In the normal control group, 106 cases were positive and 4 cases were positive. The positive rate was 3. 77% (4/106). There was significant difference between the two groups (P <0.01). Conclusion Pregnant women with abnormal pregnancy history are more likely to be infected with cytomegalovirus again, and the cause should be identified before pregnancy. Early diagnosis and early treatment should be done to reduce the chance of re-birth.