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目的了解漯河市农村妇女宫颈癌前病变及宫颈癌的发病情况,为制定有效的预防措施提供理论依据和技术支持。方法应用液基细胞学检查技术并结合TBS分级系统,采用随机原则于2012年3-6月对漯河市20个农村5 919例妇女进行免费宫颈癌筛查,对非典型鳞状细胞(ASC)及其以上病变行道镜检查并取病理学活检。结果共筛查5 919例妇女,异常439例(7.42%),30~35岁组及42~47岁组妇女患病率高。其中未见上皮内病变或癌变(NILM)5 480例(92.58%),ASC288例(4.87%)[ASC包括意义不明确的非典型性鳞状细胞(ASCUS)268例(4.53%)和不除外高级别鳞状上皮内病变(ASCH)20例(0.34%)],低级别鳞状上皮内病变(LSIL)96例(1.62%),高级别鳞状上皮内病变(HSIL)51例(0.86%),鳞状上皮癌(SCC)4例(0.07%)。对140例ASC以上病例行道镜检查并取活检做病理组织学诊断,其中正常或炎症82例(58.57%)、CINⅠ14例(10.00%)、CINⅡ10例(7.14%)、CINⅢ29例(20.71%)、浸润癌(ISCC)5例(3.57%)。结论液基细胞学检查技术结合TBS分级系统是筛查宫颈病变的有效手段;农村妇女宫颈疾病,特别是高级别病变发病率高,应重视农村妇女宫颈癌预防与普查工作。
Objective To understand the incidence of cervical precancerous lesions and cervical cancer in rural women in Luohe City and provide theoretical basis and technical support for the development of effective preventive measures. Methods Using liquid-based cytology and TBS grading system, we randomly selected 5919 women from 20 rural areas in Luohe City from March to June 2012 to conduct screening of cervical cancer for atypical squamous cell (ASC) And more than the pathological examination and biopsy pathology biopsy. Results A total of 5 919 women were screened, 439 (7.42%) were abnormal, and the prevalence was high in women aged 30-35 and 42-47 years. Of these, 5,480 (92.58%) had no intraepithelial neoplasia or carcinogenesis (NILM), 28 (4.87%) had ASC [ASC including 268 (4.53%) of ASCUS with undefined significance and There were 96 cases (1.62%) of low grade squamous intraepithelial lesion (LSIL) and 51 cases (0.86%) of high grade squamous intraepithelial lesion (ASCH) ), Squamous cell carcinoma (SCC) in 4 cases (0.07%). There were 82 cases (58.57%) of normal or inflammation, 14 cases of CIN (10.00%), 10 cases of CINⅡ (7.14%), 29 cases of CINⅢ (20.71%), Invasive carcinoma (ISCC) in 5 cases (3.57%). Conclusion liquid-based cytology combined with TBS grading system is an effective means of screening for cervical lesions; rural women with cervical disease, especially high-grade lesions with high incidence, should pay attention to rural women’s cervical cancer prevention and census.