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目的进一步了解象山县出生缺陷发生情况,以利于实施出生缺陷干预工程。方法监测2005年1月1日至2009年12月31日所有产妇分娩的胎儿在孕期和产后7 d内发现的出生缺陷的相关情况,统一上报,并进行调查、分析。结果 2005-2009年共出生24 863名胎儿,出生缺陷发生率为147.61/万;发生死胎170例,其中缺陷儿死胎占65.88%;孕28周后发现的出生缺陷占88.01%,孕28周前发现的占11.99%;按系统分类排在前5位的分别为循环系统先天性畸形,肌肉骨骼系统先天性畸形和变形,眼、耳、面和颈部先天性畸形,神经系统先天性畸形,唇裂和腭裂。结论 5年出生缺陷发生率总体呈逐年上升趋势,死胎出生缺陷发生率明显高于活胎发生率,孕28周前发现的出生缺陷所占的比例逐年增大,做好三级预防措施是关键。
Objective To further understand the birth defects in Xiangshan County in order to facilitate the implementation of birth defects intervention project. Methods The fetuses born during the period from January 1, 2005 to December 31, 2009 were detected during pregnancy and 7 days after delivery. The cases were reported uniformly and investigated. Results A total of 24,863 fetuses were born in 2005-2009, with a birth defect rate of 147.61 / million. There were 170 stillbirths, of which 65.88% were stillborn babies; 88.01% were born defects after 28 weeks’ gestation and 28.01% Found in 11.99%; according to the system ranked in the top 5 were congenital circulatory system deformity, musculoskeletal system congenital malformations and deformation, eye, ear, face and neck congenital malformations, congenital malformations of the nervous system, Cleft lip and cleft palate. Conclusions The incidence of 5-year birth defects shows a year-by-year upward trend. The incidence of stillbirths is significantly higher than that of live births. The proportion of birth defects found before 28 weeks of pregnancy is increasing year by year. It is the key to make tertiary prevention measures .