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目的观察 2 9例高凝疾患者饮用碱性离子水前、后 ,血粘度、凝血因子、纤溶指标及血小板聚集率的变化。方法饮用碱性离子水前、后 (2～ 3个月、>3～ 6个月 )作低切变率 (1/10 s)及高切变率 (1/12 0 s)。全血粘度(ηb)、血浆粘度 (ηp)、纤维蛋白原 (Fg)、凝血因子 ∶活性 ( ∶ C)、血管性假血友病因子抗原 (v WF∶ Ag)、D-二聚体 (DD)及血小板聚集率 (PAg R)测定。结果饮碱性离子水后增高的低切变率及高切变率 ηb、ηp、Fg、 ∶ C、v WF∶ Ag及 PAg R水平均有不同程度下降 ,尤其是低切变率ηb、ηp、 ∶ C、v WF∶ Ag及 PAg R下降尤为明显 ,P值均小于 0 .0 5～ 0 .0 0 1。结论饮碱性离子水后红细胞及血小板解聚 ,凝血改善以及血管内皮损害的修复 ,进一步改善了血液流通及微循环灌注 ,减少了血栓形成的机会 ,因而有利于对心、脑血管血栓性疾患的防治。
Objective To observe the changes of blood viscosity, coagulation factors, fibrinolysis indexes and platelet aggregation rate before and after drinking alkaline ion water in 29 patients with hypercoagulable disease. Methods Before and after drinking alkaline ionized water, low shear rate (1/10 s) and high shear rate (1/12 0 s) were used for 2 ~ 3 months and> 3 ~ 6 months. Whole blood viscosity (ηb), plasma viscosity (ηp), fibrinogen (Fg), clotting factors: activity (: C), vWF: Ag, D-dimer DD) and platelet aggregation rate (PAg R). Results The results showed that the low shear rate and the high shear rate ηb, ηp, Fg ,: C, v WF: Ag and PAg R after drinking alkaline ionized water all decreased to different degrees, especially the low shear rate ηb, ηp : C, v WF: Ag and PAg R decreased especially significantly, all P values were less than 0.05 ~ 0.010. CONCLUSIONS: Decontamination of erythrocytes and platelets, improvement of coagulation and repair of vascular endothelial lesions after alkaline ionized water improves the blood circulation and microcirculation perfusion and reduces the chances of thrombosis, which is good for cardiovascular and cerebrovascular thrombosis Prevention and treatment.