论文部分内容阅读
对36例(72耳)新生儿缺氧缺血性脑病(HIE)以及22例(44耳)正常新生儿进行听觉脑干诱发反应(ABR)及诱发性耳声发射(EOAES)检测。HIE病人ABR异常34耳(47.2％),EOAES异常31耳(51.4％)。对照组异常耳数0和3耳(6.8％)。通过检测发现在轻度HIE病人中EOAES异常耳数较ABR高(17∶12),提示轻度HIE病人耳蜗外毛细胞受损率高。并随着脑部损害加重异常耳数明显增加。同时提示重度HIE病人脑干受损及毛细胞受损率相当高。两种方法属无创性,并能客观地反映听力及脑干功能、及耳蜗外毛细胞受损情况。通过检测能准确确定受损部位,及时给予治疗可减少后遗症的发生。
Auditory brainstem response (ABR) and evoked otoacoustic emission (EOAES) were measured in 36 cases (72 ears) of neonates with hypoxic-ischemic encephalopathy (HIE) and 22 cases (44 ears) of normal neonates. Abnormal ABR of 34 ears (47.2%) in HIE patients and 31 ears (51.4%) of abnormal EOAES. The control group of abnormal ear 0 and 3 ears (6.8%). EIAES abnormal ear count in mild HIE patients was higher than that of ABR (17:12), suggesting that mild HIE patients had high cochlear outer hair cell loss. And with increased brain damage abnormal ear significantly increased. At the same time suggest that patients with severe HIE brain stem damage and hair cell damage is quite high. Both methods are noninvasive, and can objectively reflect the hearing and brainstem function, and hair loss of cochlear hair cells. Detection can accurately determine the damaged site, timely treatment can reduce the incidence of sequelae.