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自60年代以来,六氯对二甲苯即为国内外治疗华支睾吸虫病的首选特效药。尽管该药治愈率较其他药为高,但副作用也大,因此,国内外学者都在寻求新特效药,以取代六氯对二甲苯。近几年来,国内外同仁在肯定了吡喹酮对血吸虫病和绦虫病疗效的同时,也对感染了华支睾吸虫的动物和病人,进行了治疗研究。但各家用药剂量、疗程和疗效均不一致,这给大规模普治华支睾吸虫病带来了困难,为此,我们于1982年6～12月,在山东青岛地区,从27,800余人的普查中,查出华支睾吸虫病人(部分为感染者)277例,进行了治疗观察,以探讨在本地区保持最好疗效的合适剂量与疗程,研究结果较为满意,现报告如下:
Since the 1960s, hexachloroparaxylylene is the preferred drug of choice for the treatment of Clonorchiasis at home and abroad. Although the cure rate is higher than other drugs, but the side effects are also large, so domestic and foreign scholars are looking for new drug to replace hexachloroparaxylylene. In recent years, colleagues at home and abroad have affirmed the efficacy of praziquantel against schistosomiasis and taeniasis, and also treated animals and patients infected with Clonorchis sinensis. However, the dose of each drug, treatment and efficacy are inconsistent, which gives large-scale Pruhonosoriasis Clostridosis has brought difficulties, therefore, we from June 1982 to December in Qingdao, Shandong Province, more than 27,800 people from the census , 277 cases of Clonorchis sinensis (partially infected) were identified and treated to observe the appropriate dose and course of treatment to maintain the best curative effect in the region. The results of the study are satisfactory and are reported as follows: