目的探讨婴儿迁延性腹泻的病因及其与肠道菌群变化的关系。方法选择 6个月～ 1岁迁延性腹泻患儿 35例和对照组健康婴儿 31例 ,对他们进行肠道菌群定量培养分析和致病菌培养。结果 35例患儿粪便中 ,双歧杆菌与对照组比较明显降低 ,肠球菌升高 (P <0 .0 1)。结论婴儿迁延性腹泻中多数病例是肠道菌群紊乱所致。 Objective To investigate the etiopathogenisis of infantile persistence diarrhea and its relationship with intestinal microflora. Methods 35 children with persistent diarrhea from 6 months to 1 year old and 31 healthy infants from the control group were enrolled in this study. Quantitative analysis of intestinal microflora and pathogen culture were conducted. Results Among 35 cases of children, Bifidobacterium was significantly decreased compared with the control group, and enterococci were increased (P <0.01). Conclusions Most cases of persistent diarrhea in infants are caused by disturbances of the intestinal microflora.