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目的探讨早期微量喂养与全静脉营养在新生儿机械通气中的应用效果。方法将2010年3月至2015年3月82例危重新生儿机械通气者作为实验对象,采用随机法分成实验组与对照组,每组41例,实验组患儿采取早期微量喂养,对照组患儿采取全静脉营养,比较分析两组患儿机械通气时间、体质量恢复花费时间、喂养耐受状况及不良反应出现情况等。结果实验组与对照组患儿机械通气时间、体质量恢复花费时间比较差异未见统计学意义(P>0.05)。实验组患儿喂养耐受率为85.37%,对照组为43.90%,实验组喂养耐受率明显高于对照组,差异有统计学意义;实验组患者不良反应坏死性小肠结肠炎、胃功能紊乱等发生率显著低于对照组(P<0.05),但两组患者不良反应腹胀、胃潴留发生率比较差异未见统计学意义。结论早期微量喂养在新生儿机械通气治疗中具有更好的应用效果,与全静脉营养相比,其有效地提高了患儿喂养耐受率,降低了胃肠功能异常发生几率,安全高效,值得使用与推广。
Objective To explore the effect of early micronutrient feeding and total parenteral nutrition on neonatal mechanical ventilation. Methods From March 2010 to March 2015, 82 cases of critically ill neonatal mechanical ventilator were divided into experimental group and control group by random method, with 41 cases in each group. The experimental group took early micro-feeding and the control group Children take the whole vein nutrition, comparative analysis of two groups of children with mechanical ventilation time, body weight recovery time, feeding tolerance and adverse reactions and so on. Results There was no significant difference between the experimental group and the control group in the time spent on mechanical ventilation and body weight recovery (P> 0.05). The tolerance rate of experimental group was 85.37% and that of control group was 43.90%. The tolerance rate of experimental group was significantly higher than that of control group, the difference was statistically significant. In experimental group, the incidence of necrotizing enterocolitis and gastric dysfunction (P <0.05), but there was no significant difference between the two groups in the incidence of abdominal distension and gastric retention. Conclusion Early micronutrient feeding in neonatal mechanical ventilation has a better effect, compared with the whole parenteral nutrition, which effectively improve the feeding rate of children, reduce the risk of gastrointestinal dysfunction, safe and efficient, it is worth Use and promotion.