原发性肝癌(肝癌)是一种恶性程度高、早期浸润和转移性强的肿瘤,我国发病人数约占全球的55%;在肿瘤相关死亡中仅次于肺癌,位居第二。早期肝癌患者接受根治性治疗(包括手术切除、肝移植、射频消融),5年生存率高达70%。然而,70%左右的肝癌患者就诊时已是中晚期,只能接受姑息性介入、射频消融、放疗等非手术治疗,严重影响其预后。本文就 Primary liver cancer (HCC) is a kind of malignant tumor with early invasion and metastasis. The incidence in China accounts for about 55% of the global total. It is second only to lung cancer in cancer-related deaths. Patients with early liver cancer underwent radical treatment (including surgical resection, liver transplantation, radiofrequency ablation), 5-year survival rate of up to 70%. However, about 70% of patients with liver cancer are already in advanced stages of treatment, and can only accept palliative intervention, radiofrequency ablation, radiotherapy and other non-surgical treatment, seriously affecting their prognosis. This article is