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目的:回顾分析肾移植术后巨细胞病毒性肺炎(CMV)的临床特点,探讨预防和诊治巨细胞病毒肺炎的方法,提高人肾存活率。方法:对2000年1月～2007年12月肾移植术后发生的56例CMV肺炎患者的临床特点及诊疗措施进行回顾性分析。结果:56例患者,肺炎发生在术后6个月以内37例,28例患者表现为急性呼吸窘迫综合征,经抗病毒等综合治疗后39例患者治愈,人肾存活,17例死亡,其中12例死于呼吸功能衰竭,5例死于严重混合感染。平均住院时间32天。结论:由于CMV肺炎病情凶险,强调早期预防、早期诊断及早期应用抗CMV药物等综合治疗方法,针对不同的患者采取不同的诊疗策略,适当调整免疫抑制方案、改善肺功能及加强支持治疗均能有效的促进病情的恢复。
OBJECTIVE: To retrospectively analyze the clinical features of cytomegalovirus pneumonia (CMV) after renal transplantation and to explore ways to prevent and treat CMV pneumonia and improve the survival rate of human kidney. Methods: The clinical features and diagnosis and treatment of 56 patients with CMV pneumonia after renal transplantation from January 2000 to December 2007 were analyzed retrospectively. Results: Of the 56 patients, 37 cases were diagnosed as having pneumonia within 6 months after operation, 28 patients showed acute respiratory distress syndrome, 39 patients were cured after comprehensive treatment with antivirus and so on. Renal kidney survived and 17 died 12 died of respiratory failure, 5 died of serious mixed infection. The average length of stay is 32 days. CONCLUSION: Due to the dangerous condition of CMV pneumonia, the comprehensive treatment of early prevention, early diagnosis and early application of anti-CMV drugs is emphasized, different treatment strategies are taken for different patients, the immunosuppressive regimen is appropriately adjusted to improve lung function and supportive treatment Effectively promote the recovery of the disease.