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【目的】了解益生菌与中医辨证法对小儿轮状病毒肠炎的疗效。【方法】将120例轮状病毒肠炎患儿随机分为中医治疗组、益生菌组和对照组,每组各40例。3组患儿均给予常规基础治疗(包括合理喂养,预防和纠正脱水),在此基础上,中医治疗组根据中医辨证分型分别给予分证施治(湿热证者给予葛根芩连汤加减,风寒证者给予藿香正气散加减,伤食证者给予保和丸加减,脾虚证者给予参苓白术散加减),益生菌组给予双歧杆菌三联活菌胶囊治疗,对照组给予思密达口服治疗,每天记录3组患儿的大便次数、性状等临床症状,于治疗后第3天及第5天进行疗效分析。【结果】(1)治疗3 d后,3组患儿的总有效率均达100%,差异无统计学意义(P>0.05);但治疗3 d后的显效率比较,中医治疗组的治疗效果显著优于益生菌组及对照组,差异均有统计学意义(P<0.05)。(2)治疗3 d和5 d后,3组患儿的腹泻次数均较治疗前明显减少(P<0.05),且中医治疗组在改善腹泻次数方面明显优于益生菌组及对照组,差异均有统计学意义(P<0.05)。(3)中医治疗组的平均病程明显短于益生菌组和对照组,差异均有统计学意义(P<0.05)。【结论】对于轮状病毒肠炎,中药辨证施治疗效明确,可以更快地减少大便次数和缩短病程。
【Objective】 To understand the effect of probiotics and syndrome differentiation on pediatric rotavirus enteritis. [Methods] 120 cases of rotavirus enteritis were randomly divided into TCM treatment group, probiotics group and control group, 40 cases in each group. The three groups of children were given routine basic treatment (including reasonable feeding, prevention and correction of dehydration), on this basis, Chinese medicine treatment group according to TCM syndrome differentiation were given sub-syndromes (damp-heat syndrome given Gegen Qinlian Decoction, Cold syndrome were given Huoxiangzhengqisan addition and subtraction, injury food permit given Baohe pills addition and subtraction, spleen deficiency were given Shenling Baizhu San addition and subtraction), probiotic group given Bifidobacterium triple viable capsule treatment, the control group given Smectite oral treatment, daily record of 3 groups of children stool frequency, traits and other clinical symptoms, in the first 3 days and 5 days after treatment efficacy analysis. 【Results】 (1) After 3 days of treatment, the total effective rate of all three groups reached 100%, the difference was not statistically significant (P> 0.05); However, after 3 days of treatment, The results were significantly better than the probiotics group and the control group, the difference was statistically significant (P <0.05). (2) After 3 days and 5 days of treatment, the number of diarrhea in 3 groups was significantly lower than that before treatment (P <0.05), and TCM treatment group was significantly better than probiotics group and control group in improving diarrhea frequency All were statistically significant (P <0.05). (3) The average course of TCM treatment group was significantly shorter than the probiotics group and the control group, the difference was statistically significant (P <0.05). 【Conclusion】 For rotavirus enteritis, the curative effect of TCM syndrome differentiation and treatment is clear, which can reduce stool frequency and shorten the course of disease more quickly.