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目的观察高频通气膈肌起搏（ＨＤＰ）对慢性阻塞性肺病（ＣＯＰＤ）治疗作用。方法１９例ＣＯＰＤ病人给予ＨＤＰ治疗。结果ＨＤＰ可增加伴有或不伴有呼吸衰竭的ＣＯＰＤ患者ＰａＣＯ２、ＳａｔＯ２膈肌活动度和潮气量，而对ＰａＣＯ２、口腔最大吸气压、口腔最大呼气压无明显的影响。结论ＨＤＰ对ＣＯＰＤ有较好的治疗作用，短时治疗对呼吸肌功能无明显的影响。
Objective To observe the therapeutic effect of high frequency ventilation diaphragmatic pacing (HDP) on chronic obstructive pulmonary disease (COPD). Methods Nineteen COPD patients were treated with HDP. Results HDP increased PaCO2 and SatO2 diaphragmatic activities and tidal volume in COPD patients with or without respiratory failure, while had no significant effect on PaCO2, maximal oral pressure and maximal oral expiratory pressure. Conclusions HDP has a good therapeutic effect on COPD. Short-term treatment has no significant effect on respiratory muscle function.