嘌呤核苷是嘌呤核苷酸降解途径中的中间体,它的生物学作用引起研究者的重视。1972年首先发现人的腺苷代谢先天性异常与重症联合型免疫缺损病(SCID)有关,数年后又注意到2′-脱氧腺苷的毒性作用。十年来对腺苷的一些生物学性质作了检定,它对哺乳类动物细胞和细菌细胞有毒性,它的存在 Purine nucleosides are intermediates in the purine nucleotide degradation pathway, and its biological role has drawn the attention of researchers. In 1972, it was first discovered that the congenital anomalies of adenosine metabolism in humans are related to severe combined-type immunodeficiency disease (SCID). A few years later, the toxic effects of 2’-deoxyadenosine were also noted. A few years on the biological properties of adenosine made a test, it is toxic to mammalian cells and bacterial cells, its existence