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对 175例心脑血管病变患者检测血浆脂蛋白 (a) [L p(a) ]、氧化低密度酯蛋白 (OXL DL )和一氧化氮(NO)的含量并与年龄相匹配的健康老年人及服用氟伐他汀前后的血浓度进行对比 ,结果表明 ,观察组 L p(a)、OXL DL;较对照组增高 ,NO较对照组下降 (P<0 .0 5 ) ;氟伐他汀使用前后对照 ,用药后 L p(a)、OXL DL 减低 ,NO增高 ,前后比较差异显著 (P<0 .0 5 )。 L p(a)、OXL DL和 NO可预示动脉粥样硬化的存在 ,氟伐他汀酶确具降脂作用。
A total of 175 patients with cardiovascular and cerebrovascular diseases were measured for plasma lipoprotein (a) [L p (a)], oxidized low density lipoprotein (OXL DL) and nitric oxide (NO) And before and after taking fluvastatin compared the results showed that the observation group L p (a), OXL DL; higher than the control group, NO decreased compared with the control group (P <0.05); before and after the use of fluvastatin Control, L p (a), OXL DL decreased, NO increased significantly after treatment (P <0.05). L p (a), OXL DL and NO can predict the presence of atherosclerosis, and fluvastatin is indeed lipid-lowering.