论文部分内容阅读
目的:观察用利福平注射液治疗肺结核的疗效。方法:将2010年1月至2011年1月我院收治的60例肺结核患者随机分为观察组和对照组。为观察组患者使用利福平注射液进行治疗,为对照组患者使用利福平口服片剂进行治疗,对比两组患者的临床疗效,并对其用药的起效时间、治疗周期、药物吸收率、用药不良反应等进行观察。结果:两组患者的病情均得到不同程度的改善,其治疗的总有效率相比较差异不显著(p>0.05),无统计学意义。与对照组患者相比,应用利福平注射剂进行治疗的观察组患者其起效时间、治疗周期、药物吸收率等方面的指标均较优,差异显著,具有统计意义(p<0.05)。在两组患者中分别有3例患者出现恶心、呕吐的不良反应,其发生不良反应的几率均为10%。结论:用利福平治疗肺结核的疗效确切。与应用利福平口服片剂相比,应用利福平注射液治疗肺结核起效较快,用药周期较短,药物吸收率较高,更值得在临床上推广使用。
Objective: To observe the efficacy of rifampin injection in the treatment of pulmonary tuberculosis. Methods: From January 2010 to January 2011, 60 cases of pulmonary tuberculosis admitted to our hospital were randomly divided into observation group and control group. The patients in the observation group were treated with rifampicin for the treatment, and the patients in the control group were treated with oral tablets of rifampicin. The clinical efficacy of the two groups of patients was compared. The onset time, the treatment cycle, the rate of drug absorption , Adverse drug reactions such as observation. Results: The two groups of patients were treated with different degrees of improvement, the total effective rate was not significantly different (p> 0.05), no statistical significance. Compared with the control group, the patients in observation group treated with rifampin injection had better performance in terms of onset time, treatment cycle and drug absorption rate, with significant difference (p <0.05). In the two groups of patients, respectively, 3 patients showed nausea and vomiting adverse reactions, the incidence of adverse reactions were 10%. Conclusion: The efficacy of rifampicin in the treatment of pulmonary tuberculosis is exact. Compared with the oral application of rifampicin tablets, the application of rifampin injection treatment of tuberculosis rapid onset, shorter medication cycles, higher drug absorption, more worthy of promotion in clinical use.