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目的探讨小剂量氟哌利多和地西泮联合米非司酮米索用于大月份钳刮术的应用效果。方法 200例自愿要求人工流产术患者,随机分为观察组和对照组,各100例。观察组患者静脉应用小剂量氟哌利多联合地西泮下进行钳刮手术,对照组患者应用丙泊酚麻醉下进行手术。分别监测两组麻醉诱导时间、镇痛效果、定向力恢复时间、体动分级、宫颈软化情况、出血量及术中患者心率(HR)、血氧饱合度(Sp O2)、手术前后血压(BP)。结果两组麻醉效果、体动表现、宫颈软化程度、术前宫深及手术时间对比,差异均无统计学意义(P>0.05);但两组术中HR变化≥30%、Sp O2≤90%、手术前后BP变化≥30%的例数及子宫收缩程度、出血量相比,差异均具有统计学意义(P<0.05)。结论氟哌利多和地西泮联合米非司酮米索用于大月份钳刮术,对呼吸循环影响小,不影响子宫收缩、手术出血量少。
Objective To investigate the effect of low-dose droperidol and diazepam combined with mifepristone misoprostol on large-month forceps curettage. Methods 200 cases of voluntary abortion patients were randomly divided into observation group and control group, each 100 cases. Patients in the observation group were treated with small-dose droperidol and diazepam in the vein, and the control group was operated under anesthesia with propofol. The anesthesia induction time, analgesic effect, recovery time of oriental force, body movement classification, cervical softening, amount of bleeding and intraoperative patients heart rate (HR), oxygen saturation (Sp O2), blood pressure before and after surgery ). Results There was no significant difference between the two groups in anesthesia, body movement, degree of cervical softening, depth of preoperative anteroposterior and operative time (P> 0.05). However, HR changes in the two groups were ≥30% and Sp O2 ≤90 %, The number of BP changes ≥30% before and after surgery and the number of uterine contractions, the amount of bleeding, the differences were statistically significant (P <0.05). Conclusion Droperidol and diazepam combined with mifepristone misoprostol for large month curettage, little effect on the respiratory cycle, does not affect the uterine contraction, less bleeding surgery.