目的　探讨宫颈湿疣的临床类型及组织病理学特征与人乳头瘤病毒 (HPV)亚型的关系。方法　对 130例宫颈湿疣进行病理形态学观察 ,同时采用PCR技术进行HPV6 /11、HPV16 /18检测。结果　扁平型宫颈湿疣与HPV6 /11感染密切相关 (P <0⒈ 0 1) ,凹空细胞呈轻度异型性。乳头型宫颈湿疣与HPV16 /18密切相关 (P <0 0 1) ,凹空细胞呈重度异型性。结论　宫颈湿疣的临床类型及组织病理学特征与HPV亚型密切相关 ,对HPV16 /18所致的乳头型宫颈湿疣应积极治疗和随访。 Objective To investigate the clinical and histopathological features of cervical condyloma and its relationship with human papillomavirus (HPV) subtypes. Methods 130 cases of cervical condyloma were observed by pathomorphology, and HPV6 / 11 and HPV16 / 18 were detected by PCR. Results Flat type condyloma acuminatum was closely related to HPV6 / 11 infection (P <0 ⒈ 0 1). Concave cells were mild atypia. Papillary condyloma acuminatum is closely related to HPV16 / 18 (P <0.01), and concave cells are heavily atypia. Conclusion The clinical types and histopathological features of cervical condyloma are closely related to the subtype of HPV, and should be actively treated and followed up for HPV16 / 18 caused papillary genital warts.