β-阻滞剂和扩血管药对肝硬化患者门静脉血流的影响

来源 :国外医学(消化系疾病分册) | 被引量 : 0次 | 上传用户:zhengjunzhe
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β-阻滞剂心得安、扩皿管药消心痛等,已被用于预防肝硬化复发性消化道出血,其作用似与降低门静脉压力有夫。肝门静脉压力的高低,决定于其血流量和肝内阻力;药物可降低前者血流量,但不影响肝内阻力。近来新的超声显象仪问世,可测定腹腔深部血管的血流量和速度。作者应用这种非侵入性方法评价心得安、氨酰心安、消心痛对肝硬化伴重度食管静脉曲张并有高度出血危险患者的门静脉血流的短期作用。患者和方法:肝硬化代偿期患者8名,男3、女5。平均年龄62岁。其中酒精性4例,肝炎后2例,原因不明2例,食管静脉均明显曲张,有高度出血危险而以往 β-blocker propranolol, such as angina pectoris, has been used to prevent cirrhosis of recurrent gastrointestinal bleeding, its role and reduce the pressure of the portal vein husband. Hepatic portal vein pressure, depending on its blood flow and intrahepatic resistance; drugs can reduce the former blood flow, but does not affect intrahepatic resistance. Recently, the advent of a new ultrasound system, can be measured deep blood vessels in the abdominal cavity blood flow and speed. The authors use this noninvasive method to evaluate the short-term effects of propranolol, atenolol, and acetochlor on portal blood flow in cirrhotic patients with severe esophageal varices and at high risk of bleeding. Patients and Methods: Eight patients with decompensated cirrhosis, 3 males and 5 females. The average age is 62 years old. Of which alcohol 4 cases, 2 cases after hepatitis, 2 cases of unknown cause, esophageal vein were significantly varicose, with a high risk of bleeding in the past
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