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目的探讨小牛血去蛋白提取物在IV期糖尿病肾病患者中的应用价值。方法将46例Ⅳ期糖尿病肾病患者随机分为对照组和治疗组,治疗组23例予以小牛血去蛋白提取物400 mg静脉滴注,1次/d,连续2周。其余用药与对照组一致。观察用药前后患者血肌酐及尿素氮水平,血糖及肝功情况。结果治疗组血肌酐及尿素氮水平较用药前下降,而对照组则有不同程度升高。结论小牛血去蛋白提取物对IV期糖尿病肾病患者有确切疗效,未发现不良反应。
Objective To investigate the value of deproteinized calf blood serum in patients with stage IV diabetic nephropathy. Methods Forty-six patients with stage Ⅳ diabetic nephropathy were randomly divided into control group and treatment group. In the treatment group, 23 cases were treated with intravenous infusion of deproteinized calf serum 400 mg once daily for 2 weeks. The rest of the medication and the control group. Before and after treatment observed serum creatinine and urea nitrogen levels, blood glucose and liver function. Results Serum creatinine and blood urea nitrogen levels in the treatment group decreased compared with those before treatment, while those in the control group increased to some extent. Conclusion The deproteinized calf blood extract has the exact effect on patients with stage IV diabetic nephropathy, and no adverse reactions were found.