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JAKs (januskinase/ justanotherkinase)是由JAK1~3,TYK2四个成员构成的一个家族 ,属于非受体型酪氨酸蛋白激酶 ,是细胞因子受体介导信号传导途径中的重要信号分子 ,由细胞因子诱导的细胞因子受体复合物活化。广泛参与了淋巴细胞的发育
JAKs (januskinase/justanotherkinase) is a family consisting of four members of JAK1-3, TYK2. It belongs to the non-receptor type tyrosine protein kinase and is an important signal molecule in the cytokine receptor-mediated signaling pathway. Factor-induced cytokine receptor complex activation. Widely involved in the development of lymphocytes