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目的验证临床药师对我院中药注射剂合理使用进行干预的效果。方法对比分析2010年临床药师干预前后中药注射剂的合理使用情况,随机抽取2010年1-6月合格病历1 000份,设为非干预组;随机抽取2010年9月-2011年2月合格病历1 000份,设为干预组;评估临床药师的干预作用。结果非干预组中药注射剂的使用率为31.10%,干预组为19.00%,差异有统计学意义(χ2=38.991,P=0.000);非干预组适应证不合理的为6.00%,干预组为2.10%,差异有统计学意义(χ2=19.570,P=0.000);非干预组发生不良反应15例,干预组发生3例,两组不良反应发生率差异有统计学意义(χ2=8.073,P=0.004);中药注射剂的用法用量趋于规范。结论临床药师对中药注射剂临床使用的干预行之有效,对促进医院安全、有效、合理使用中药注射剂起到了积极作用。
Objective To verify the effect of clinical pharmacists on rational use of Chinese medicine injection in our hospital. Methods A comparative analysis of rational use of traditional Chinese medicine injections before and after the intervention of clinical pharmacists in 2010, randomly selected 1 000 copies of qualified medical records from January to June in 2010 as non-intervention group; randomly selected from September 2010 to February 2011 qualified medical records 1 000, as the intervention group; assessment of clinical pharmacist intervention. Results The non-intervention group was 31.10% for the injection of Chinese medicine and 19.00% for the intervention group, the difference was statistically significant (χ2 = 38.991, P = 0.000). The non-intervention group was 6.00% with unreasonable indications and 2.10 %, The difference was statistically significant (χ2 = 19.570, P = 0.000); 15 cases of adverse reactions in non-intervention group, 3 cases in intervention group, the difference was statistically significant (χ2 = 8.073, P = 0.004). The usage of traditional Chinese medicine injection tends to be standardized. Conclusion The clinical pharmacists’ intervention in the clinical use of traditional Chinese medicine injection has been effective and has played a positive role in promoting the safe, effective and rational use of traditional Chinese medicine injections in hospitals.