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左旋咪唑目前为驱虫首选药。常见的副作用有头痛、头晕、失眠、恶心,腹部不适,个别病例有发热,但高热反应报道不多,现将我们遇到的2例(3次)报告如下。例1:黎某,男,31岁。因间歇性上腹部疼痛3年,于1984年5月3日入院。体检:体温37℃,脉搏74次,血压110/80。心肺(-),腹软,右上腹压痛(+),肝脾未触及。血尿常规检查正常,大便常规蛔虫卵18个/片。诊断为:(1)十二指肠球部溃疡;(2)肠道蛔虫感染。于5月7日及8日晚各服左旋咪唑150mg,8日突然高热,体温39.2℃,白细胞总数为10,550,中性为82%,其他体征同前。因当时未考虑到系左旋咪唑所致,故给予补液、青霉素肌肉注射,2日后体温恢复正常。因未见排虫,故于25日晚又口服150mg,当晚体温升至39.3℃,经对症处理1天后体温降至正常。
Levamisole is currently the preferred drug for deworming. Common side effects are headache, dizziness, insomnia, nausea, abdominal discomfort, individual cases have fever, but few reports of hyperthermia, now we encounter 2 cases (3 times) reported as follows. Example 1: Li Mou, male, 31 years old. Due to intermittent upper abdominal pain for 3 years, on May 3, 1984 admission. Physical examination: body temperature 37 ℃, pulse 74 times, blood pressure 110/80. Heart and lung (-), abdominal soft, right upper quadrant tenderness (+), liver and spleen not touched. Normal examination of hematuria, stool routine Ascaris eggs 18 / piece. Diagnosis: (1) duodenal ulcer; (2) intestinal Ascaris infection. Levamisole 150 mg was given on the 7th and the 8th of each night. Suddenly high fever on the 8th was 39.2 ° C. The total number of white blood cells was 10,550. The neutrality was 82%. Other signs were the same as before. Because at that time did not take into account the Department of levamisole, it is given rehydration, intramuscular injection of penicillin, body temperature returned to normal after 2 days. Because there is no row of worms, so on the evening of 25 and oral 150mg, body temperature rose to 39.3 ℃ night, after symptomatic treatment 1 day after the temperature dropped to normal.