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目的 :探讨抗心肌ADP/ATP载体 (ANT)抗体对小儿心脏病的诊断价值。方法 :运用免疫印转法检测了 3 0例病毒性心肌炎 (VMC)、14例扩张型心肌型 (DCM) ,10例风湿性心脏病 (RHD)、2 2例先天性心脏病 (CHD)患儿血浆抗ANT水平。结果 :抗ANT抗体在VMC和DCM患儿中的阳性率显著高于RHD、CHD和NC三组研究对象 (P均 <0 .0 1)。抗ANT抗体诊断VMC和DCM的敏感性为 72 73 % ,特异性为 98 2 5 %。结论 :抗ANT抗体在小儿心脏病的鉴别诊断中有重要价值 ,可作为小儿VMC和DCM的特异性诊断指标
Objective: To investigate the diagnostic value of anti-myocardial ADP / ATP carrier (ANT) antibody in children with heart disease. Methods: 30 cases of viral myocarditis (VMC), 14 cases of dilated cardiomyopathy (DCM), 10 cases of rheumatic heart disease (RHD), 22 cases of congenital heart disease (CHD) Plasma anti-ANT levels. Results: The positive rates of anti-ANT antibody in VMC and DCM were significantly higher than those in RHD, CHD and NC (all P <0.01). The anti-ANT antibody had a sensitivity of 72 73% and a specificity of 98 2 5% for the diagnosis of VMC and DCM. Conclusion: Anti-ANT antibody has important value in the differential diagnosis of pediatric heart disease and can be used as a specific diagnostic indicator of pediatric VMC and DCM