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综述微生物基因组研究对于深化认识微生物之间关系的作用以及利用微生物基因组开发抗感染性疾病的主要手段和进展,其中重点是利用生物信息学手段、基因芯片、噬菌体表面展示系统筛选新的抗微生物药物作用靶点。
This review summarizes the roles of microbial genomes in deepening the understanding of the relationship among microorganisms and the major approaches and advances in the development of anti-infective diseases using microbial genomes. The focus is on the screening of new antimicrobial agents using bioinformatics tools, gene chips and phage display systems Targets