急性淋巴细胞白血病(ALL)合并抽搐与疾病的严重性和药物所致脑病有关,其发生机理尚不明了。回顾1,289例接受中枢神经系统预防处理的ALL病儿,其中132例(10%)于病程中有过1次或多次惊厥发作。36例可找到明确的惊厥诱因:细胞破坏加剧引起代谢紊乱9例,血小板减少所致颅内出血 Acute lymphoblastic leukemia (ALL) with convulsions and the severity of the disease and drug-induced encephalopathy, the pathogenesis is not yet clear. A retrospective review of 1,289 children with ALL who received CNS prophylaxis was conducted, of which 132 (10%) had one or more seizures during the course of the disease. 36 cases can find a clear cause of seizures: increased cell damage caused by metabolic disorders in 9 cases, intracranial hemorrhage caused by thrombocytopenia