心房颤动是临床最常见的持续性心律失常,其中非瓣膜性心房颤动占心房颤动的绝大多数,血栓栓塞是心房颤动最常见的并发症。抗凝治疗可减少血栓栓塞并发症,但增加了出血的风险。因此,对血栓栓塞危险性进行评估,筛选出高危患者有选择地进行抗凝治疗尤为重要。本文从血液标志物、心电图f波、超声心动图、64排CT及临床因素等方面对非瓣膜性心房颤动患者血栓栓塞危险性研究现状及进展作一综述。 Atrial fibrillation is the most common persistent arrhythmia in clinical practice. Non-valvular atrial fibrillation accounts for the vast majority of atrial fibrillation. Thromboembolism is the most common complication of atrial fibrillation. Anticoagulant therapy reduces thromboembolic complications but increases the risk of bleeding. Therefore, the assessment of the risk of thromboembolism, screening for high-risk patients with selective anticoagulant therapy is particularly important. This review summarizes the research status of thromboembolism risk in patients with nonvalvular atrial fibrillation from blood markers, electrocardiogram f wave, echocardiography, 64-slice CT and clinical factors.