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目的研究分析早期介入治疗在颅内动脉瘤破裂预后治疗中的临床应用价值。方法将我院于2011年3月至2012年9月收治的86例颅内动脉瘤破裂患者按照血管内治疗距发病时间分组,分为早期介入治疗组(血管内治疗距发病时间<72h)、晚期介入治疗组(血管内治疗距发病时间>72h),每组n=43,比较两组患者术后栓塞程度及预后评价。结果早期介入治疗组患者栓塞治疗效果明显高于晚期介入治疗组,P<0.05,大部分栓塞(栓塞程度>90%)、部分栓塞(栓塞程度<90)情况对比有显著差异,P<0.05。早期介入治疗预后良好35例,预后不良8例;晚期介入治疗组预后良好27例,预后不良18例。两组预后评价对比P<0.01,具有统计学意义。结论早期介入治疗能够取得较好的治疗效果及造影完全栓塞程度高,预后良好率显著,是颅内动脉瘤破裂预后治疗的首选治疗时机。
Objective To study the clinical value of early interventional therapy in prognosis of intracranial aneurysm rupture. Methods Totally 86 patients with ruptured intracranial aneurysms who were treated in our hospital from March 2011 to September 2012 were divided into two groups: early intervention group (intravascular treatment less than 72 hours) The late intervention group (endovascular treatment from onset time> 72h), n = 43 in each group, the embolization degree and prognosis of the two groups were compared. Results In the early intervention group, the effect of embolization was significantly higher than that of the late intervention group (P <0.05). Most embolization (degree of embolism> 90%) and partial embolization (degree of embolization <90) showed significant difference, P <0.05. Early interventional treatment of good prognosis in 35 cases, 8 cases of poor prognosis; late interventional treatment group, a good prognosis in 27 cases, 18 cases of poor prognosis. The prognosis of two groups were compared P <0.01, with statistical significance. Conclusion Early interventional therapy can achieve better therapeutic effect and embolization of embolism with a high degree of good prognosis, is the preferred treatment of intracranial aneurysm rupture prognosis of treatment.