病原微生物及能激活体液和细胞免疫过程的非感染性抗原均可引起口腔粘膜的炎症。大多数口腔粘膜炎产生白细胞反应,形成粘膜下细胞浸润,在一定程度上,还可蔓延至上皮内。钙保护素(calprotectin)是一种来源于白细胞的二聚体蛋白质复合物,有较强的抗菌和抗真菌作用。最近在皮肤和粘膜的角质细胞中发现 Pathogenic microorganisms and non-infectious antigens that activate both humoral and cellular immune processes can cause inflammation of the oral mucosa. Most oral mucositis produce leukocyte reaction, the formation of submucosal cell infiltration, to some extent, can also spread to the epithelium. Calprotectin is a leukocyte-derived dimeric protein complex that has strong antibacterial and antifungal effects. Recently found in cutaneous and mucosal keratinocytes