论文部分内容阅读
目的了解儿童甲型H1N1流感合并肺炎的临床特点。方法回顾性分析资料完整的5例甲型H1N1流感合并肺炎的患儿临床表现、实验室检查和影像学资料。采取患儿鼻咽拭子标本,冰壶保存立即送深圳市疾病预防控制中心,采用实时逆转录核酸扩增聚合酶链反应CRT-PCR进行甲型H1N1流感病毒核酸检测。结果 5例患儿4例以发热起病,1例既往有哮喘病史的患儿以进行性喘息伴呼吸困难发病,24h后才开始出现发热。5例均伴有进行性咳嗽,5例病例均可听到双下肺细湿啰音,经治疗热退后肺部啰音消失缓慢瘟凭凑瘴夜郎堪洳嫉摹都仔虷1N1流感诊疗方案(2009年试行版第3版)》进行治疗,5例患儿均接受了奥司他韦抗病毒治疗,均未见明显不良反应,既往有哮喘的患儿合并呼吸衰竭和气胸,给予人工通气治疗,5例患儿均痊愈出院。结论儿童甲型H1N1流感合并肺炎患儿发热的时间较长,咳嗽较重、肺部啰音较多、消失较慢;既往有哮喘的患儿病情更加严重,临床上应给予高度重视。经给予奥司他韦抗病毒治疗后,患儿发热、咳嗽、肺部啰音改善较快?喜⒎窝椎募仔虷1N1流感比未合并肺炎的患儿住院时间要长。
Objective To understand the clinical features of children with influenza A (H1N1) and pneumonia. Methods The clinical manifestations, laboratory tests and imaging data of 5 children with influenza A (H1N1) pneumonia complicated with pneumonia were retrospectively analyzed. Take nasopharyngeal swab specimens of children, curling save immediately sent to Shenzhen Center for Disease Control and Prevention, real-time reverse transcription nucleic acid amplification polymerase chain reaction CRT-PCR for influenza A H1N1 influenza virus nucleic acid detection. Results In 5 cases, 4 cases had onset of fever. One case of children with previous history of asthma developed progressive wheezing accompanied with dyspnea and began to develop fever after 24 hours. 5 cases were accompanied by progressive cough, 5 cases can be heard double lower lung fine wet rales, fever after treatment, pulmonary rales disappear slowly disappear blast hash 瘴 night Lang Kan 洳 envy are Aberdeen 1N1 flu treatment plan (2009 trial version of the third edition) "for treatment, 5 patients were treated with oseltamivir antiviral therapy, no significant adverse reactions, with previous asthma in children with respiratory failure And pneumothorax, given artificial ventilation treatment, 5 patients were discharged from hospital. Conclusions Children with influenza A (H1N1) and pneumonia have longer fever, heavier cough, more pulmonary rales and slower disappearance. Children with previous asthma are more exacerbated and should be given high priority in clinical practice. After given oseltamivir antiviral therapy, children with fever, cough, pulmonary rales improved faster? Xi Xi Wo litter Tsai Chi 1N1 flu than children without pneumonia longer hospital stay.