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四、锂盐的作用机制:1.增加或增强 CSABarrett 认为,Li 刺激粒系造血的最可能途径就是增加 CSA 的产量。Gupta 报告,8名 Felty 综合症患者服用 Li 剂后,尿及血中的 CSA 无例外地明显增加。Harker 通过对小鼠骨髓细胞的体外培养发现:在无 CSA 存在时,Li 不能单独使
Fourth, the mechanism of action of lithium salt: 1. To increase or enhance CSABarrett that Li stimulate granulocyte hematopoiesis is the most likely way to increase CSA production. Gupta reported that urine and blood CSA increased significantly without exception after taking Li agent in eight patients with Felty’s syndrome. Harker found in vitro culture of mouse bone marrow cells that Li can not be used alone in the absence of CSA