耳硬化症始发病灶在骨迷路囊,进一步发展有新生的血管、骨密度减低,呈“海绵状’夕骨质。Linds,y论证在颜骨标本骨间隙中无活性骨细胞。这些死骨病灶导致新骨形成,有血管、细胞、海绵体和不规则的骨质排列。有破骨细胞和骨细胞活性分裂,并产生骨重建酶。 The earliest onset of otosclerosis in the bony labyrinth capsule, the further development of new blood vessels, reduced bone mineral density, was “sponge-like” edema .Linds, y demonstration of non-activated bone cells in the interosseous bone specimens of bone. The lesions lead to the formation of new bone, with blood vessels, cells, cavernous bodies and irregular bone arrangement, osteoclasts and osteoblastic activity, and the production of bone-remodeling enzymes.