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目的:旨在研究脑心通胶囊联合西医常规治疗PCI术后患者的临床研究。方法:选自邢台市人民医院2013年1月—2014年6月心内科门诊就诊或住院的PCI术后患者共120例。随机分为治疗组和对照组各60例。对照组只给予西医常规治疗,治疗组在西医常规治疗的基础上给予脑心通胶囊,疗程4周。观察治疗后的症状、体征、生活质量、心电图等变化。结果:两组治疗后,治疗组心绞痛疗效总有效率为90.00%,对照组总有效率为60.00%,差异显著。心电图疗效总有效率为90.00%,对照组总有效率为53.33%,差异显著。两组治疗后,治疗组中医证候疗效总有效率93.33%,对照组总有效率56.67%,差异显著。两组治疗后:治疗组硝酸酯类药物停用率达46.67%,停减率70.00%,对照组停用率26.7%,停减率43.3%,治疗组硝酸酯类药物的停减率明显高于对照组,差异有统计学意义。两组治疗后,两组患者生存质量在总体健康、身体疼痛、活力、精神健康、健康变化比较,差异有统计学意义。在生理功能、生理职能、社会功能、情感比较,差异无统计学意义。结论:步长脑心通胶囊能够显提高心绞痛疗效,提高中医证候疗效,提高心电图疗效,改善患者的生活质量。
Objective: To study the clinical study of Naoxintong Capsule combined with Western routine treatment of patients after PCI. Methods: A total of 120 patients were selected from Xingtai People’s Hospital January 2013 to June 2014 out-patient or in-patient PCI. Randomly divided into treatment group and control group of 60 cases. The control group was given routine treatment of Western medicine. The treatment group was given Naoxintong capsule on the basis of routine treatment of Western medicine for 4 weeks. Observed after treatment symptoms, signs, quality of life, ECG changes. Results: After treatment, the total effective rate of angina pectoris in treatment group was 90.00%, while the total effective rate in control group was 60.00%, the difference was significant. The total effective rate of electrocardiogram was 90.00%, the total effective rate of the control group was 53.33%, the difference was significant. After treatment, the total effective rate of TCM syndromes in the treatment group was 93.33%, while that of the control group was 56.67%, the difference was significant. After treatment, the rate of discontinuation of nitrates in the treatment group was 46.67%, the rate of reduction was 70.00%, the rate of discontinuation in the control group was 26.7% and the rate of reduction was 43.3%. The reduction rate of nitrates in the treatment group was significantly higher In the control group, the difference was statistically significant. After treatment, the quality of life of the two groups was statistically significant in overall health, body aches, vitality, mental health and health. In the physiological function, physiological function, social function, emotional comparison, the difference was not statistically significant. Conclusion: Bu Tong Naoxintong Capsule can significantly improve the efficacy of angina pectoris, improve TCM curative effect, improve electrocardiogram curative effect and improve patient quality of life.