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“肠—胰岛轴”一词是试图用来说明胃肠道和胰腺内分泌之间存在着相互作用。目前的实验资料认为,在消化时,抑胃肽可能是来自小肠的促进胰腺内分泌活动的主要生理性信息,通过肠—胰岛轴,引起胰岛释放胰岛素、胰高血糖素、胰多肽或生长抑素。反之,胰腺内分泌对肠道激素也具有反馈性影响。
The term “gut-islet axis” is intended to indicate that there is an interaction between the gastrointestinal tract and pancreatic endocrine. The current experimental data suggest that at digestion, gastric inhibitory peptide may be from the small intestine to promote pancreatic endocrine activity of the main physiological information through the gut-islet axis, causing islet release of insulin, glucagon, pancreatic polypeptide or somatostatin . Conversely, pancreatic endocrinology also has a feedback effect on intestinal hormones.