原发性血小板增多症(PT)为慢性型巨核细胞系肿瘤性增殖疾患。临床以原因不明的血小板显著持续增多,出血和血栓形成及脾肿大为主要症侯。近年来随着对血小板形态、生化、生理机能和代谢研究的进展,对本病的概念和认识亦得到相应的深化。现结合Gunz(1960)和服部(1973—1977)各综合报导的50例资料,并归纳最近文献就本病出血机理与临床研究作一概述。 Primary thrombocythemia (PT) is a chronic proliferative disease of the megakaryocytic cell line. Clinical unexplained platelets continued to increase significantly, bleeding and thrombosis and splenomegaly as the main symptoms. In recent years, with the progress of research on platelet morphology, biochemistry, physiology and metabolism, the concept and understanding of this disease have also been deepened accordingly. Now combined with Gunz (1960) and Kubu Department (1973-1977) of the 50 cases of comprehensive data, and summarized the recent literature on the bleeding mechanism and clinical studies made an overview.