重症急性胰腺炎(Severe Acute Pancreatitis SAP)是一临床概念,其含义为(1)死亡,(2)重症监护7天以上,(3)伴发局部或全身伴发症保守治疗无效者,约占急性胰腺炎(Acute Pancreatitis SP)发病总数的4～16%。其中急性出血坏死性胰腺炎(Acute Hemorrhagic Necrotizing Pancreatitis,AHNP)占80%左右。SAP临床经过凶险,死亡发生率高达40～70%, Severe acute pancreatitis (Severe Acute Pancreatitis SAP) is a clinical concept, the meaning of (1) death, (2) intensive care more than 7 days, (3) with conservative treatment of local or systemic complications ineffective, accounting for about Acute Pancreatitis (Acute Pancreatitis SP) incidence of 4 to 16% of the total. Acute Hemorrhagic Necrotizing Pancreatitis (AHNP) accounted for about 80%. SAP clinically dangerous, the incidence of death as high as 40 to 70%