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目的:探讨阿奇霉素在急性肠炎治疗中的应用及临床疗效。方法:选取我院在2010年6月-2013年期间收治的78例急性肠炎患者,并将所选取的患者分为两组,观察组的40例患者采用阿奇霉素注射液进行治疗,对照组的38例患者采用培氟沙星注射液进行治疗,然后对两组患者的临床疗效进行观察和对比。结果:观察组的治疗总有效率为97.8%,对照的治疗总有效率仅为74.3%;观察组治疗的显效率为91.4%,对照组治疗的显效率仅为67.5%。两组患者在治疗的总有效率以及显效率之间均有明显的差异(P<0.05)观察组的临床疗效明显比对照组好,详见表1。且观察组患者症状好转、止泻时间以及症状消失的时间都明显比对照组短(P<0.05);两组患者都没有出现明显的不良反应。结论:采用阿奇霉素对急性肠炎患者进行治疗,具有起效快、临床疗效好、不良反应少等多个优点,而且使用方便、价格低、安全性高,可以作为临床上治疗急性肠炎的优选药物。
Objective: To investigate the application and clinical efficacy of azithromycin in the treatment of acute enteritis. Methods: Seventy-eight patients with acute enteritis admitted to our hospital from June 2010 to 2013 were enrolled and divided into two groups. Forty patients in the observation group were treated with azithromycin injection. In the control group, 38 Patients with pefloxacin injection for treatment, and then the clinical efficacy of two groups were observed and compared. Results: The total effective rate of the observation group was 97.8%, while that of the control group was only 74.3%. The effective rate of the observation group was 91.4%. The effective rate of the control group was only 67.5%. There was a significant difference between the two groups in the total effective rate and the markedly effective rate (P <0.05). The clinical efficacy of the observation group was obviously better than that of the control group. See Table 1 for details. The symptom improvement, diarrhea time and disappearance of symptoms in the observation group were significantly shorter than those in the control group (P <0.05). No obvious adverse reactions occurred in both groups. Conclusion: Azithromycin has the advantages of rapid onset, good clinical curative effect and few adverse reactions. It is easy to use, low in price and high in safety. It can be used as the preferred drug for the treatment of acute enteritis in clinic.