基础胰岛素是糖尿病患者控制血糖的有力武器,然而,医生及患者在胰岛素起始及剂量优化过程中的顾虑限制了其作用的发挥。地特胰岛素是一种具有良好降糖效果的基础胰岛素,研究显示其在个体内变异性低、低血糖风险较低,并可减少体重增加,这些特征增加了地特胰岛素剂量优化的可行性,对糖尿病患者的血糖管理具有重要意义。 Basal insulin is a powerful weapon for the control of blood sugar in diabetic patients. However, the concerns of physicians and patients during insulin initiation and dose optimization limit their effectiveness. Dextrins, a basal insulin with a good hypoglycemic effect, have been shown to have low intra-individual variability, low hypoglycaemia risk and reduced weight gain, all of which add to the viability of detemir dose optimization, It is of great importance to the blood sugar management in diabetic patients.