Objective To investigate the factors that influence the potential for cryoembryo implantation and multiple pregnancy. Methods In this retrospective study, a total of 937 thawing cycles (859 couples) in which 3286 d 3-embryos were thawed. Rates of implantation, clinical pregnancy and multiple conception following FET were observed. Results There were significant differences in female age (P<0.05) and number of good quality embryos (P<0.05) between cycles that resulted in pregnancy and those did not. There was a trend toward decreasing rates of implantation, clinical pregnancy and multiple pregnancy with increasing female age. Compared with transferring 1 good quality embryo, clinical pregnancy rate of transferring 2 and 3 good quality embryos was increased significantly (P<0.001), there was no significant difference in clinical pregnancy rate between transferring 2 and 3 good quality embryos. Multiple pregnancy rate was increased significantly in the group of transferring 3 good quality embryos (P<0.05),but there was no significant differences in multiple pregnancy rate between transferring 1 and 2 good quality embryos.Younger women (≤ 30 years) also had a significantly higher multiple pregnancy rates (28.13%) than the older ones(>35 years) (13.64%).With an increase in age from ≤ 30 years to>40 years, clinical pregnancy rate declined from 45.61% to 25.00%. Conclusion Female age and the number of good quality embryos transferred are important factors influencing the clinical and multiple pregnancy rate, reducing the number of good quality embryos transferred may decrease the rate of multiple pregnancy but do not affect the clinical pregnancy rate. Objective To investigate the factors that influence that potential for cryoembryo implantation and multiple pregnancy. A total of 937 thawing cycles (859 couples) in 3286 d 3-embryos were thawed. Rates of implantation, clinical pregnancy and multiple There was a significant difference in female age (P <0.05) and number of good quality embryos (P <0.05) between cycles that resulted in pregnancy and those did not. There was a trend toward growing rates of implantation , compared with transferring 1 good quality embryo, clinical pregnancy rate of transferring 2 and 3 good quality embryos was increased significantly (P <0.001), there was no significant difference in clinical pregnancy rate between transferring 2 and 3 good quality embryos. Multiple pregnancy rate was increased significantly in the group of transferring 3 good quality embryos (P <0.05), but there was no significant differences in multiple pregnancy rates between transferring 1 and 2 good quality embryos.Younger women (≤ 30 years) also had a significantly higher multiple pregnancy rates (28.13%) than the older ones > 35 years) (13.64%). With an increase in age from ≤30 years to> 40 years, clinical pregnancy rate declined from 45.61% to 25.00%. Conclusion Female age and the number of good quality embryos transferred are important factors influencing the clinical and multiple pregnancy rate, reducing the number of good quality embryos transferred may decrease the rate of multiple pregnancy but do not affect the clinical pregnancy rate.