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目前新生儿缺氧缺血性脑病(HIE)诊断及预后评估多限于临床表现及头颅CT改变。近年在HIE动物模型中发现脑组织中兴奋性氨基酸(EAAs)神经递质谷氨酸(Glu)、天冬氨酸(Asp)在神经细胞外有大量蓄积,造成神经元坏死。作者用丹酰氯聚酰胺薄层层析法...
Currently neonatal hypoxic-ischemic encephalopathy (HIE) diagnosis and prognosis are mostly limited to clinical manifestations and CT changes. In recent years, it has been found in animal models of HIE that excitatory amino acid (EAAs) neurotransmitters glutamate (Glu) and aspartate (Asp) accumulate abundantly in nerve cells and cause neuron necrosis. Author with dansyl chloride polyamide thin layer chromatography ...