目的:探讨中西医结合治疗儿童过敏性紫癜性肾炎的临床疗效。方法:选取我院100例过敏性紫癜性肾炎患儿作为研究对象,将全部患者随机分为对照组和观察组。对照组患者采取口服强的松片和雷公藤多苷片进行治疗,观察组患者在对照组的基础上辅以中药汤剂进行治疗。结果:观察组患者的治疗总有效率好于对照组,组间比较差异显著有统计学意义(P<0.05);观察组患儿组治疗前后24h尿蛋白和血浆白蛋白比较均存在显著差异,有统计学意义(P<0.05);对照组中治疗前24h的尿蛋白量比较差异有统计学意义(P<0.05);观察组中治疗24h的血浆白蛋白与对照组比较差异有统计学意义(P<0.05)。结论:中西医结合疗法治疗儿童过敏性紫癜性肾炎的临床效果较好,不良反应发生率较低,值得在临床上进一步推广应用。 Objective: To explore the clinical efficacy of traditional Chinese and western medicine in the treatment of children with Henoch-Schonlein purpura nephritis. Methods: 100 children with Henoch-Schonlein purpura nephritis in our hospital were selected as research objects, all patients were randomly divided into control group and observation group. Patients in the control group were treated with oral prednisone tablets and tripterygium glycosides tablets. Patients in the observation group were treated with Chinese herbal decoction on the basis of the control group. Results: The total effective rate of observation group was better than that of control group, the difference between the two groups was statistically significant (P <0.05). There was significant difference of 24h urinary protein and plasma albumin before and after treatment in observation group, (P <0.05). There was significant difference in urinary albumin level between the two groups before treatment (P <0.05), and there was significant difference between the two groups (P <0.05). Conclusion: Integrative Chinese and Western medicine treatment of children with Henoch-Schonlein purpura nephritis clinical effect is good, the incidence of adverse reactions is low, it is worth further clinical application.