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目的 :为了研究绝经后妇女的雄激素水平与骨密度之间的关系。方法 :测定了 39例从未服用过雌激素和钙剂 ,其血清雌激素水平基本相同 ,但骨密度水平有一定差异的绝经后妇女的血清睾酮水平 ,并将这些妇女依骨密度水平分为正常和骨质疏松两个组。结果 :经过统计学分析 ,发现两组血清睾酮水平有非常显著的差异 (p <0 0 0 1)。经过直线回归计算和相关分析 ,发现两个组的睾酮和各自匹配的骨密度水平呈平行变化 ,线性关系良好 ,相关系数分别为 0 72及 0 75。经相关检验 ,两个p <0 0 0 1,有高度相关。将两r值进一步进行显著性检验 ,U值为 0 14,说明两组的正相关关系无显著性差异 (p>0 0 5 )。结论 :血清睾酮水平低与骨密度与骨质疏松密切相关。
Purpose: To investigate the relationship between androgen levels and bone mineral density in postmenopausal women. Methods: Serum testosterone levels of 39 postmenopausal women who had never taken estrogen and calcium and had similar levels of serum estrogen but different bone mineral density were measured and divided into three groups according to their bone mineral density Normal and osteoporosis two groups. Results: After statistical analysis, there was a very significant difference in serum testosterone levels between the two groups (p <0 0 0 1). After linear regression analysis and correlation analysis, it was found that the testosterone and their matched bone mineral density in two groups showed a parallel change with a good linear relationship, with correlation coefficients of 0 72 and 0 75 respectively. After the correlation test, two p <0 0 0 1, there is a high degree of correlation. The two r values for further significance test, U value of 0 14, indicating no significant difference between the two groups (p> 0.05). Conclusion: Low serum testosterone levels are closely related to bone mineral density and osteoporosis.