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原发性肾小球肾炎在治疗上依然是个难题,虽然近年对病因治疗,激素加化疗在某些病例的缓解率有所提高,同时也见到大量资料证实这种联合疗法主要抑制机体免疫功能及损伤机体对细菌及病毒的正常防卫功能,感染的反复出现又是肾炎达到缓解的一大障碍。1972年Mallick及Soothill通过试验证明肾炎的发生是免疫功能低下,即抗体未能清除抗原(所谓低亲和力),普遍性T细胞功能缺陷、
Primary glomerulonephritis in the treatment is still a difficult problem, although in recent years, the cause of treatment, hormone and chemotherapy in some cases the remission rate increased, but also to see a lot of data to confirm this combination therapy mainly inhibits immune function And damage the body’s normal defense of bacteria and viruses, the recurrence of infection is a major obstacle to remission of nephritis. In 1972, Mallick and Soothill proved that nephritis was immunocompromised by experiments, ie, the antibody failed to clear the antigen (so-called low affinity), the general function of T cells was defective,